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Better Sleep

Pain Relief

Decreased Stress

Improved Immunity

Learn more about our 4 Board-Certified MD founders

Learn how MDbio products restore your endocannabinoid balance and maximize health

MDrelief

The scientifically-tested supplement to help relieve your chronic pain.

Clinically Proven Formula

Includes FullSpectrum Hemp

Non-intoxicating & non-drowsy

25% off on all orders

Reschedule, hold, or cancel at any time

FREE priority shipping

60-day money-back guarantee

Product Details

Ingredient List

How to Use

MDrelief

MDrelief
MDrelief
MDrelief
MDrelief
MDrelief
MDrelief

Doctor
fomulated

Patient

tested

Sustainably
sourced

Cruelty

free

Non

intoxicating

Non
GMO

Tackle pain and body aches naturally

“I gained wonderful relief without addictive painkillers.”

— Betty E.

  • Full spectrum hemp
  • Premium plant-based ingredients
  • Hundreds of phytochemicals
  • Doctor-developed optimal blend
  • Tested with real patients
  • Safe alternative pharmaceuticals
  • Not psychoactive
  • Restores balance
  • Supports internal ECS system
  • Premium plant-based ingredients
  • Hundreds of phytochemicals
  • Doctor-developed optimal blend
  • Tested with real patients
  • Safe alternative pharmaceuticals
  • Not psychoactive
  • Restores balance

Proven results

The efficacy of MDrelief + hemp formula has been scientifically proven through observational studies and is currently in clinical trial.

The efficacy of MDrelief botanical blend has been scientifically proven through observational studies.

In an observational study

85%
Reported a positive experience

Within 10 days

Our observational study

In an observational study

63%
Reported a positive experience

Within 10 days

Our observational study

Our ingredient list

MDrelief + hemp formula is made of sustainably sourced, non-intoxicating ingredients containing hundreds of phytochemicals.

MDrelief botanical blend is made of sustainably sourced, non-intoxicating ingredients containing hundreds of phytochemicals.

Check out our MDrelief botanical blend that features our proprietary rest complex and bio-terpene complex.

See botanical blend


*MDrelief botanical blend does not contain full spectrum hemp.

Check out our MDrelief + hemp formula that includes full spectrum hemp

See + hemp

Our solutions work with

The endocannabinoidsystem.

Discovered in in the 1990s, the Endocannabinoid system (ECS) is a sophisticated biological “control system.”

It is a complex matrix of cell receptors, neurotransmitters and enzymes that all work together to maintain homeostasis.

The largest system of biochemical receptors in our body, ECS is made of 3 parts:

Endocannabinoids in our body interact with specific parts of our cells called endocannabinoid receptors. These receptors are found on different types of cells in our body and can cause different reactions when activated. Scientists have studied two of these receptors of importance for the effects of endocannabinoids.

  • Cannabinoid 1 (CB1) Receptors: They are primarily found in the central nervous system, especially in neurons or nerve cells in the brain. THC and anandamide also bind with these receptors.
  • Cannabinoid 2 (CB2) Receptors: Found in the peripheral nervous system and immune cells. They are like tiny keyholes unlocked by molecules called 2-AG. The CB2 receptors can help reduce inflammation and other immune responses.

Endocannabinoids are natural chemicals our bodies make, similar to those found in cannabis plants. Our body produces endocannabinoids when required rather than in advance. The nervous system uses these chemicals to communicate with different body parts. 

Your body can produce these chemicals because they come from fats – everyone has an active ECS system. Dr. Larian outlines the role of an endocannabinoid in regulating nervous impulses: “When these nerves feel that the previous nerve is firing too hard… the extra input sends an endocannabinoid. This extra chemical… …goes backward and tells the nerve, ‘Calm down. You’re working too hard. Go back to your baseline and restart.’” 

Scientists have extensively researched two significant types of endocannabinoids: 

  • The messenger or "bliss" molecule: Arachidonoyl ethanolamide (anandamide or AEA)
  • 2-AG: 2-arachidonoyl glycerol enhances the function of CB1 receptors and is the primary natural molecule that can bind to CB2 receptors.

Enzymes are natural substances our bodies produce to create and break down certain chemicals. For example, when a cell needs to send a message, endocannabinoids are made by breaking down fats with the help of enzymes. After the endocannabinoids do their job, they are removed from the cells by a particular protein and broken down further by other enzymes. Regarding endocannabinoids, two types of enzymes help break them down so they don't stay in our body for too long: 

  • Fatty acid amide hydrolase (FAAH): findings suggest that FAAH has a natural ability to break down anandamide and 2-AG.
  • Monoacylglycerol acid lipase (MAG-L): Once the 2-AG molecule has completed its function, it is taken back into the cells and broken down by an enzyme called MAGL. The body uses the broken-down product to produce other compounds.

Understanding how these enzymes work could help create new treatments for diseases like addiction.

Learn more
218 Reviews
Real reviews by real people who take MDrelief
average rating 4.9 out of 5
Based on 218 reviews
  • 5 Stars
    198 Reviews
  • 4 Stars
    17 Reviews
  • 3 Stars
    0 Reviews
  • 2 Stars
    1 Review
  • 1 Star
    2 Reviews
218 Reviews
Reviewed by Edward G.
Verified Buyer
I recommend this product
Age Range
65+
Symptoms
  • Pain
Product Qualities
  • Fast-Acting
  • Does the Job
  • Effective
Rated 5 out of 5
Review posted

WORKS!!

Thanks to MDbio, I no longer have to take Advil to relieve back pains I get periodically. As a result, I do not have the problems that come with Advil or aspirin - bleeding and ulcers. This is a much safer solution, and it works brilliantly!!

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Reviewed by Christine b.
Verified Buyer
I recommend this product
Age Range
55 - 64
Symptoms
  • Pain
Product Qualities
  • Effective
  • Fast-Acting
  • Does the Job
  • Useful
  • Helpful
Rated 5 out of 5
Review posted

the only thing

this is the only thing that works for my pain in the world idk why but I know it works

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Reviewed by Shirley R.
Verified Buyer
I recommend this product
Age Range
65+
Symptoms
  • Pain
Product Qualities
  • Does the Job
Rated 5 out of 5
Review posted

What a GREAT products...

I take two MB Relief in morning and then 2 MB Sleep at night. What a difference it has made. Takes that edge off my pain and helps me to relax and fall asleep. Thanks...

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Ask Us Anything.


We’re an Open Book.

We put a lot of thought into creating these optimal blends for top conditions. Our team of doctors and experts are happy to answer your questions.

Truthfully, anytime! But we recommend you pop MDrelief with a meal. Digesting food gets those natural ingredients on the move faster.

Every body has its own universe. Start with 2 softgels for 3 days, and then adjust depending on how you have felt. If you need an extra softgel with each dose because two wasn’t doing the trick, take 3. If you have been experiencing mild side effects such as grogginess, decrease to 1 softgel per dose. The key to finding a therapeutic dose of MDbio products is through consistency. 

"Full Spectrum" is our way of saying we're embracing all the good stuff from the hemp plant (including trace amounts of THC). It’s like a team: everyone brings something unique to the table. And just like our bodies have evolved over ages with a built-in system (the “endocannabinoid” system) that touches everything we do, we believe that harnessing the full power of hemp makes the perfect tag team.

Patience. Nature's not always instant. Double-check the playbook (dosing guidelines) to make sure you're on track.

This question is for your primary care physician. Have a chat with your doctor to make sure you’re in the clear.

Talk with a live support agent by clicking on the bubble in the bottom right hand screen

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