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Decreased Stress

Improved Immunity

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Learn how MDbio products restore your endocannabinoid balance and maximize health

MDrelief

+hemp

The scientifically-tested supplement to help relieve your chronic pain.

Relieve general aches and pain

Support joint and muscle function

Includes full spectrum hemp and white willow bark

15% off on all subscription orders

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Product Details

A clinically proven blend of natural ingredients designed to decrease pain and the underlying inflammation. Carefully designed with White Willow Bark Extract, Full Spectrum Hemp, Frankincense, Boswellia Serrata, Vitamin E and many other botanicals.

Ingredient List

How to Use

Take at the first sign of discomfort, 2-3 softgels every 6 hours. Do not exceed 6 softgels per day and do not take with NSAIDs. See our full dosing guidelines here

MDrelief

MDrelief™ Hemp Blend
MDrelief™ Hemp Blend
MDrelief™ Hemp Blend
MDrelief™ Hemp Blend
MDrelief™ Hemp Blend
MDrelief™ Hemp Blend
Product Image

Tackle pain and body aches naturally

MDrelief +hemp is a potent, all herbal pain relief supplement for those looking for an alternative to NSAID painkillers. Formulated with time tested herbs such as Full Spectrum Hemp, White Willow Extract and Frankincense, it works on general aches and pains by reducing inflammation throughout the body.

Why MDrelief Hemp?

  • Includes full spectrum hemp
  • Non-psychoactive
  • Activates the endocannabinoid system
  • Natural alternative to NSAID pain relievers
  • Supports joint and muscle function
  • Supports joint and muscle function
  • Helps to reduce inflammation throughout the body
  • Relieves PMS and general pelvic pain

Our Formulas

  • Made with quality, time tested herbs and botanicals
  • Doctor Formulated
  • Cruelty Free
  • Patient Tested
  • Safe alternative pharmaceuticals

Scientifically formulated
to relieve pain

MDrelief +hemp relieves general body aches and pain by reducing inflammation throughout the body.

Full Spectrum Hemp
a clinical, non-intoxicating dose (less than 0.3 THC) activates the endocannabinoid system that regulates physiological and cognitive processes including pain relief by activating key receptors that alleviate behavioral responses to inflammatory and neuropathic pain.
Geranylgeranoiol
an important ingredient that helps the body replenish CoQ10, K12 and skeletal muscle proteins, which can protect against age-related physical decline and reverse muscle fatigue. White Willow Extract - a natural pain reliever and works like aspirin to reduce inflammation, relieving aches and fever.
Frankincense
anti-inflammatory effects that prevent the production of hormone-like substances in the body that trigger joint inflammation.

Proven Results

The efficacy of MDrelief +hemp formula has been scientifically proven through observational studies and a double-blind placebo-controlled clinical trial.

We invested in the largest 'general pain' clinical trial in history with 1,160 participants

Sleep

57%

Wellbeing

57%

Anxiety

57%

Stress

57%

Our solutions work with

The endocannabinoid system.

Our solutions work with the endocannabinoid system. Discovered in the 1990’s, the Endocannabinoid System (ECS) is a sophisticated biological “control system”. 

Is it a complex matrix of cell receptors, neurotransmitters and enzymes that all work together to maintain homeostasis. 

The largest system of biochemical receptors in our body, ECS is make of 3 parts: 

Endocannabinoids in our body interact with specific parts of our cells called endocannabinoid receptors. These receptors are found on different types of cells in our body and can cause different reactions when activated. Scientists have studied two of these receptors of importance for the effects of endocannabinoids.


  • Cannabinoid 1 (CB1) Receptors: They are primarily found in the central nervous system, especially in neurons or nerve cells in the brain. THC and anandamide also bind with these receptors.


  • Cannabinoid 2 (CB2) Receptors: Found in the peripheral nervous system and immune cells. They are like tiny keyholes unlocked by molecules called 2-AG. The CB2 receptors can help reduce inflammation and other immune responses.

Endocannabinoids are natural chemicals our bodies make, similar to those found in cannabis plants. Our body produces endocannabinoids when required rather than in advance. The nervous system uses these chemicals to communicate with different body parts.

Your body can produce these chemicals because they come from fats – everyone has an active ECS system. Dr. Larian outlines the role of an endocannabinoid in regulating nervous impulses: “When these nerves feel that the previous nerve is firing too hard… the extra input sends an endocannabinoid. This extra chemical… …goes backward and tells the nerve, ‘Calm down. You’re working too hard. Go back to your baseline and restart.’”

Scientists have extensively researched two significant types of endocannabinoids: 

  • The messenger or "bliss" molecule: Arachidonoyl ethanolamide (anandamide or AEA)
  • 2-AG: 2-arachidonoyl glycerol enhances the function of CB1 receptors and is the primary natural molecule that can bind to CB2 receptors.

Enzymes are natural substances our bodies produce to create and break down certain chemicals. For example, when a cell needs to send a message, endocannabinoids are made by breaking down fats with the help of enzymes. After the endocannabinoids do their job, they are removed from the cells by a particular protein and broken down further by other enzymes. Regarding endocannabinoids, two types of enzymes help break them down so they don't stay in our body for too long: 

  • Fatty acid amide hydrolase (FAAH): findings suggest that FAAH has a natural ability to break down anandamide and 2-AG.
  • Monoacylglycerol acid lipase (MAG-L): Once the 2-AG molecule has completed its function, it is taken back into the cells and broken down by an enzyme called MAGL. The body uses the broken-down product to produce other compounds.


Understanding how these enzymes work could help create new treatments for diseases like addiction.

Learn more

Looking for our
botanical blend?

MDreliefTM botanical

It combines a harmonizing blend of traditionally time-tested herbs with key amino acids to promote and prolong restful sleep.

Shop now

Still unsure about choosing
hemp or botanical?

1 Reviews
Real reviews by real people who take MDrelief

average rating 5.0 out of 5
Based on 1 review
  • 5 Stars
    1 Review
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100% of reviewers would recommend this product to a friend
1 Review
Reviewed by Jenna H.
Verified Buyer
I recommend this product
Age Range
45 - 54
Symptoms
  • Pain
  • Sleeplessness
Product Qualities
  • Effective
Rated 5 out of 5
Review posted

Very effective

I've used many things for chronic pain. This one really helps me sleep.

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Ask Us Anything.

We’re an Open Book.

We put a lot of thoughts into creating these optimal blends for top chronic conditions. Our team of doctors and experts are happy to answer your questions.

Can I get addicted to MDrelief?

MDrelief has plant-based ingredients that do not cause addiction or withdrawal unlike pharmaceutical pain medications.

When should I take MDrelief?

Truthfully, anytime! But we recommend you pop MDrelief with a meal. Digesting food gets those natural ingredients on the move faster.

How much should I take?

Everybody has its own universe. Start with 2 softgels for 3 days, and then adjust depending on how you have felt. If you need an extra softgel with each dose because two wasn’t doing the trick, take 3. If you have been experiencing mild side effects such as grogginess, decrease to 1 softgel per dose. The key to finding a therapeutic dose of MDbio products is through consistency.

How long does the effect last?

Depending on the severity of pain, the effect can last anywhere from 4 hours to 6 hours. We recommend taking MDrelief at the first sign of discomfort, 2-3 softgels every 6 hours. And do not exceed 6 softgels per day.

Can I take MDrelief with my other medications for pain?

We recommend that you only take one type of medication for pain and do not take with NSAIDs.

Why did you add Full Spectrum Hemp to MDrelief and what does it do?

"Full Spectrum" is our way of saying we're embracing all the good stuff from the hemp plant (including trace amounts of THC). It’s like a team: everyone brings something unique to the table. And just like our bodies have evolved over ages with a built-in system (the “endocannabinoid” system) that touches everything we do, we believe that harnessing the full power of hemp makes the perfect tag team.

What if I still don’t feel the desired effects after my first day of use?

Patience. Nature's not always instant. Double-check the playbook (dosing guidelines) to make sure you're on track.

Will this product interfere with my current medications?

This question is for your primary care physician. Have a chat with your doctor to make sure you’re in the clear.

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